ESR1 Mastery: From Mutation Monitoring to Targeted Treatment in ER+/HER2- Metastatic Breast Cancer

Harold J. Burstein, MD, PhD, is a Professor of Medicine at Harvard Medical School, and a medical oncologist at Dana-Farber Cancer Institute and Brigham & Women's Hospital. Dr. Burstein attended Harvard College, and earned his MD at Harvard Medical School where he also earned a PhD in immunology. He additionally has a master's degree in history of science from Harvard. He trained in internal medicine at Massachusetts General Hospital and in medical oncology at Dana-Farber. His clinical research interests include novel treatments for early- and advanced-stage breast cancer, and studies of quality of life and health behavior among women with breast cancer. Dr. Burstein has written widely on breast cancer in both traditional medical journals and on the web. Representative publications can be found in the New England Journal of Medicine, the Journal of Clinical Oncology, and other leading medical journals. He serves on international breast cancer committees including the NCCN Breast Cancer Panel, The St. Gallen Breast Cancer Panel, and the Alliance Breast Cancer Committee, and chairs the ASCO guidelines on endocrine therapy for breast cancer. Dr. Burstein is an Associate Editor for Cancer Education at the Journal of Clinical Oncology.

Ian S. Hagemann, MD, PhD, is a professor of pathology & immunology and of obstetrics & gynecology at Washington University in St. Louis, with interests in gynecologic, breast and molecular pathology. His clinical activity is as a surgical pathologist. His research interests are in gynecologic cancers and in the implementation of next-generation sequencing for clinical diagnostics. He is a member of the AJCC Expert Panel for gynecologic cancer staging, the Steering Committee for the landmark endometrial cancer study GOG-210, and the tissue core co-director for the Route 66 SPORE in Endometrial Cancer. In the medical school, he leads the Genetics and Genomics Thread and a senior-level elective in precision medicine, and is the Assistant Dean for Admissions. Medical students at Washington University and pathology residents at the University of Pennsylvania have selected him for several teaching awards.